The onset of early osteoarthritis is most commonly preceded by damage to joint articular cartilage. This damage can be mapped via biochemical-based MRI techniques, such as T2 mapping, T1 rho (spin lattice relaxation in the rotating frame) imaging and delayed gadolinium- enhanced MRI of cartilage (dGEMRIC) [2]. These modalities assess the microstructure of hyaline cartilage to visualize early signs of degeneration or disorganization, as these signs are normally absent on plain film radiographs. Presumably, with the aid of these modalities, osteoarthritis can be diagnosed earlier, thus allowing for apt implementation of potential prevention strategies.